f = open('/tmp/workfile', 'r+')
f.write('0123456789abcdef')
f.seek(5)     # Go to the 6th byte in the file
f.read(1)
f.seek(-3, 2) # Go to the 3rd byte before the end
f.read(1)
f.readline()
f.close()
		

for line in open("myfile.txt"):
    print line

with open("myfile.txt") as f:
    for line in f:
        print line